Publications

Citing TCP

Please acknowledge the contributions of TCP staff and resources in your presentations and published work.

In the acknowledgements section, e.g., “The authors wish to acknowledge the contribution of the [service core e.g. Model Production, Pathology] at The Centre for Phenogenomics for [activity – e.g colony management, generation of mutant mice, phenotyping, histology]”.

Or in the methods section, e.g., “[Activity/Resource] was performed/provided by [service core] at The Centre for Phenogenomics”.

For all animal studies performed at TCP, “All procedures on animals at The Centre for Phenogenomics (TCP) were reviewed and approved by TCP’s Animal Care Committee. TCP is certified by the Canadian Council on Animal Care and registered under the Animals for Research Act of Ontario.”

Immunofluorescence image of embryonic day 6.25 mouse embryos expressing Oct4-mCherry, H2B-GFP and DAPI
Immunofluorescence image of embryonic day 6.25 mouse embryos expressing Oct4-mCherry, H2B-GFP and DAPI

Research Spotlight

Posfai et al. 2020. Evaluating totipotency using criteria of increasing stringency. Nature Cell Biology 23:49-60.

Research from the lab of Dr. Janet Rossant at The Hospital for Sick Children re-assessed the totipotency of two recently published embryonic stem cell lines by comparing transcriptomes, gene regulatory networks and developmental potential with pre- and post-implantation mouse embryos. This work sets a new “gold standard” framework with which to assess totipotency in future analyses.

Congratulations to the authors and thank you for your gracious acknowledgement of TCP.

Publications