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The Centre for Phenogenomics
The Centre for Phenogenomics

Pathology Fees

Gross Pathology

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Gross Pathology Table One
Gross pathology Canadian academic International academic
Whole-body necropsy (no perfusion)/mouse (includes images) $62.10 $99.36
Whole-body necropsy (perfusion)/mouse (no images) $136.28 $218.04
Perfusion only/mouse (no images) $86.25 $138.00
Euthanize & organ-specific dissection/hour $62.10 $99.36
Embryo(s) & placenta(s) removal (max 8/litter) $189.75 $303.60

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Gross Pathology Table Two: Technical Time
Technical time Canadian academic International academic
Necropsy technologist consultation or teaching/hour $62.10 $99.36

Histology

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Histology Table One: Parrafin Processing/block
Paraffin processing/block Canadian academic International academic
Processing only $6.35 $10.16
Processing & embedding $9.11 $14.57
Trimming, processing & embedding $11.61 $18.58
Decalcify (acid based), Processing & Embedding $12.42 $19.87
Special prep. (Eg. Tissue scrolls for RNA/DNA extraction) $20.70 $33.12
Block re-embedding $2.76 $4.42

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Histology Table Two: Frozen Tissue Handling
Frozen tissue handling Canadian academic International academic
Freezing/block $5.24 $8.39

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Histology Table Three: Sectioning from Block
Sectioning from block Canadian academic International academic
Max. 3 paraffin sections/slide $3.31 $5.30
Max. 1 frozen section/slide $3.31 $5.30
Collect additional level(s) on same slide (price per additional level, max. 3 levels) $3.00 $4.80

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Histology Table Four: Routine and special histochemical staining
Routine and special histochemical staining Canadian academic International academic
H&E/slide $3.93 $6.29
Counter stain only/slide $3.73 $5.96
Special stain – simple/slide $7.52 $12.03
Special stain – complex/slide $11.87 $18.99
Enzymes/slide $11.87 $18.99
Tunel stain/slide $38.64 $61.82
Hypoxyprobe $38.64 $61.82
Histology Table Five: Immunohistochemistry/Immunofluorescence
Immunohistochemistry / Immunofluorescence Canadian academic International academic
Single IHC or IF/slide1 $24.84 $39.74
Double IF /slide1 $37.26 $59.62
Triple IF/slide1 $49.68 $79.49
New antibody (includes max. 10 trials for optimization)/antibody $281.52 $450.43
Primary antibody/slide $5.01 $8.02

1pricing is based on user providing primary antibodies, if the pathology core is providing the primary antibody then the ‘primary antibody’ charge is applied in addition to the IHC/IF staining cost.

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Histology Table Six: Technical Time
Technical time Canadian academic International academic
Histotechnologist consultation or teaching/hour $62.10 $99.36

Digital Pathology

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Digital Pathology Table: Whole tissue section slide
Whole tissue section slide scanning/slide Canadian academic International academic
20x equivalent Bright-field $5.52 $8.83
40x equivalent Bright-field $8.28 $13.25
60x equivalent Bright-field $12.42 $19.87
100x equivalent Bright-field $18.63 $29.81
20x equivalent Fluorescent $11.04 $17.66
40x equivalent Fluorescent $16.56 $26.50
60x equivalent Fluorescent $24.84 $39.74
100x equivalent Fluorescent $37.26 $59.62

Molecular Pathology

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Molecular Pathology Table Two: LacZ reporter gene expression staining
LacZ reporter gene expression staining Canadian academic International academic
Adult (includes perfusion, specialized necropsy & organ whole-mount staining)/mouse $513.48 $821.56
Adult (includes perfusion, specialized necropsy & tissue section staining)/mouse $562.19 $899.50
Embryo > E17.5 (includes tissue collection for genotyping, & embryo whole-mount staining, max. 8/litter) $1,527.20 $2,443.52
Embryo E14.5-E17.5 (includes tissue collection for genotyping, & embryo whole-mount staining, max. 8/litter) $1297.20 $2075.52
Embryo < E14.5 (includes tissue collection for genotyping, & embryo whole-mount staining, max. 8/litter) $377.20 $603.52

Histopathology

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Histopathology Table One
Histopathology Canadian academic International academic
Pathologist Consultation/hour (includes complete gross & histopathological evaluation with image-enabled electronic report, digital photomicrographs & recommendations) $133.86 $214.18
Gene Expression Annotation (per hour – includes adult tissue section histological evaluation & annotation scoring with image-enabled electronic report, digital photomicrographs of representative tissues & recommendations) $133.86 $214.18
Juvenile and Adult Mouse/mouse (includes necropsy, macroimaging, 40-tissue sample collection, histological processing of 2 decalcified & 8 soft tissue paraffin blocks, histopathological evaluation with image-enabled electronic report, digital photomicrographs & recommendations) $399.58 $639.33

Embryo analysis

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Embryo analysis One
Embryo analysis Canadian academic International academic
Embryo analysis – of embryo or pup from female mouse (includes embryo & extra-embryonic tissue collection for genotyping, morphometry, macroimaging, histological sample processing per embryo with histopathological evaluation & image-enabled electronic report) $105.82 $169.32
Embryo lethal/pregnant mouse based on max. 8 embryos/mouse (includes embryo & extra-embryonic tissue collection for genotyping, morphometry, macroimaging histological sample (embryo only) processing with histopathological evaluation & image-enabled electronic report) $677.53 $1084.05

Clinical Chemistry

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Clinical chemistry Table One
Sample collection/sample Canadian academic International academic
Whole blood collection & serum or plasma separation $38.32 $61.31
Bone marrow (femur & tibia) collection (includes impression smear & centrifuged pellet reconstitution with glycerol) $38.32 $61.31

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Organ panel or analyte Canadian academic International academic
Cardiovascular panel $20.98 $33.56
Kidney panel $20.98 $33.56
Liver panel $20.98 $33.56
All 3 organ panels $62.93 $100.68
Any single analyte from above/plasma sample $15.18 $24.29

Some analytes may be substituted between panels if required.

Add an additional 10μl (min.) for each sample to account for dead volume (dead volume requirement may vary if clots are present or hemolysis has occurred).