The Centre for Phenogenomics
The Centre for Phenogenomics

Pathology Fees

Gross Pathology

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Gross Pathology Table One
Gross pathology Canadian academic International academic
Whole-body necropsy (no perfusion)/mouse (includes images) $62.10 $99.36
Whole-body necropsy (perfusion)/mouse (no images) $136.28 $218.04
Perfusion only/mouse (no images) $86.25 $138.00
Euthanize & organ-specific dissection/hour $62.10 $99.36
Embryo(s) & placenta(s) removal (max 8/litter) $189.75 $303.60

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Gross Pathology Table Two: Technical Time
Technical time Canadian academic International academic
Necropsy technologist consultation or teaching/hour $62.10 $99.36

Histology

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Histology Table One: Parrafin Processing/block
Paraffin processing/block Canadian academic International academic
Processing only $6.35 $10.16
Processing & embedding only $9.11 $14.57
Processing, decal & embedding only $12.42 $19.87
Special preparation $20.70 $33.12
Re-embed $2.76 $4.42

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Histology Table Two: Frozen Tissue Handling
Frozen tissue handling Canadian academic International academic
Freezing/block $5.24 $8.39

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Histology Table Three: Sectioning from Block
Sectioning from block Canadian academic International academic
Paraffin or frozen/slide $3.31 $5.30

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Histology Table Four: Staining
Staining Canadian academic International academic
H&E/slide $3.93 $6.29
Counter stain only/slide $3.73 $5.96
Special stain – simple/slide $7.52 $12.03
Special stain – complex/slide $11.87 $18.99
Enzymes/slide $11.87 $18.99
Tunel stain/slide $38.64 $61.82
Hydroxyprobe $38.64 $61.82
Immunohistochemistry/slide/antibody $24.84 $39.74
New antibody (includes max. 10 trials for optimization)/antibody $281.52 $450.43
Antibody – low cost/slide $1.89 $3.02
Antibody – medium cost/slide $5.01 $8.02
Antibody – high cost/slide $8.35 $13.36

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Histology Table Five: Methyl methacrylate plastic processing/block
Methyl methacrylate plastic processing/block Canadian academic International academic
Processing & embedding $28.98 $46.37
Sectioning from plastic block/slide $20.70 $33.12
Sectioning from plastic block/additional slide $6.90 $11.04
H&E $3.93 $6.29
Goldners Trichrome $7.52 $12.03
Toluidine blue $7.52 $12.03
Tartrate-Resistant Acid Phosphatase (TRAP) stain $11.87 $18.99

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Histology Table Six: Whole tissue section slide
Whole tissue section slide scanning/slide Canadian academic International academic
20x equivalent BF $5.52 $8.83
40x equivalent BF $8.28 $13.25
20x equivalent IF $11.04 $17.66
40x equivalent IF $16.56 $26.50

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Histology Table Seven: Technical Time
Technical time Canadian academic International academic
Histotechnologist consultation or teaching/hour $62.10 $99.36

Molecular Pathology

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Molecular Pathology Table Two: LacZ reporter gene expression staining
LacZ reporter gene expression staining Canadian academic International academic
Adult (includes perfusion, specialized necropsy & organ whole-mount staining)/mouse $513.48 $821.56
Adult (includes perfusion, specialized necropsy & tissue section staining)/mouse $562.19 $899.50
Embryo > E17.5 (includes tissue collection for genotyping, & embryo whole-mount staining, max. 8/litter) $1,527.20 $2,443.52
Embryo E14.5-E17.5 (includes tissue collection for genotyping, & embryo whole-mount staining, max. 8/litter) $1297.20 $2075.52
Embryo < E14.5 (includes tissue collection for genotyping, & embryo whole-mount staining, max. 8/litter) $377.20 $603.52

Histopathology

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Histopathology Table One
Histopathology Canadian academic International academic
Pathologist Consultation/hour (includes complete gross & histopathological evaluation with image-enabled electronic report, digital photomicrographs & recommendations) $133.86 $214.18
Gene Expression Annotation (per hour – includes adult tissue section histological evaluation & annotation scoring with image-enabled electronic report, digital photomicrographs of representative tissues & recommendations) $133.86 $214.18
Juvenile and Adult Mouse/mouse (includes necropsy, macroimaging, 40-tissue sample collection, histological processing of 2 decalcified & 8 soft tissue paraffin blocks, histopathological evaluation with image-enabled electronic report, digital photomicrographs & recommendations) $399.58 $639.33

Embryo Lethal and Neonatal Death

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Embryo Lethal and Neonatal Death Table One
Embryonic lethal or neonatal death Canadian academic International academic
Embryo Lethal & Neonatal Lethal/embryo or pup from female mouse (includes embryo & extra-embryonic tissue collection, embryo tissue collection for genotyping, morphometry, macroimaging of embryo & extra-embryonic tissue, & histological sample processing per embryo with histopathological evaluation & image-enabled electronic report including digital photomicrographs & recommendations. Placenta not included.) $105.82 $169.32
Embryo Lethal/pregnant mouse based on max 8 embryos/mouse (includes embryo & extra-embryonic tissue collection, embryo tissue collection for genotyping, morphometry, macroimaging of embryos & extra-embryonic tissue, & histological sample (embryo only) processing with histopathological evaluation & image-enabled electronic report including digital photomicrographs & recommendations. Placenta not included.) $677.53 $1084.05

Clinical Chemistry

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Clinical chemistry Table One
Sample collection/sample Canadian academic International academic
Whole blood collection & serum or plasma separation (terminal retro-orbital or cardiac puncture) $38.32 $61.31
Bone marrow (femur & tibia) collection (includes impression smear & centrifuged pellet reconstitution with glycerol) $38.32 $61.31

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Organ panel or analyte Canadian academic International academic
Cardiovascular panel $20.98 $33.56
Kidney panel $20.98 $33.56
Liver panel $20.98 $33.56
All 3 organ panels $62.93 $100.68
Any single analyte from above/plasma sample $15.18 $24.29

Some analytes may be substituted between panels if required.

Add an additional 10μl (min.) for each sample to account for dead volume (dead volume requirement may vary if clots are present or hemolysis has occurred).