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The Centre for Phenogenomics
The Centre for Phenogenomics

About Us

Organization and Objectives

The Centre for Phenogenomics (TCP, formerly "Toronto Centre for Phenogenomics") is owned and operated by Mount Sinai Hospital and The Hospital for Sick Children as a centralized, state-of-the-art national research facility. Open since 2007, TCP provides animal resources, model production, clinical phenotyping, infection and inflammation, imaging, pathology, and cryopreservation and recovery services to users locally, across Canada and around the world.

TCP is a Canada Foundation for Innovation Major Science Initiative Fund (CFI-MSI) national research facility (Lead, Dr. Monica Justice) and Genome Canada Genomics Technology Platform (GTP) (Leads, Drs. Colin McKerlie and Silvia Vidal). These operations and maintenance funds enable TCP to deliver its research services nationally, facilitate collaborations, and implement and develop cutting-edge technologies to support in vivo genomics and biomedical research.

What We Do

The strength of TCP is our collective expertise and unique ability to design, generate, hold, analyze, archive, and distribute a critical mass of mouse models under one roof. We provide:

  • Custom services for the generation of genetically engineered mouse models
  • Mouse holding and technical services for preclinical in vivo research projects
  • Comprehensive or disease-specific phenotyping, host response analysis to in vivo immunological challenges and pathology services for research, and drug discovery and evaluation
  • Biorepository services to archive, acquire, and distribute mouse models

Research and Ethics

TCP is committed to the highest standards of animal ethics and care in science. All studies meet the requirements of the provincial legislation and regulations of the Animals for Research Act as well as the national guidelines and policies of the Canadian Council on Animal Care and are approved by TCP Animal Care Committee.

Leadership

Scientific Director

Dr. Monica Justice
Email: monica.justice@sickkids.ca

Senior Management Team

Dr. Lise Phaneuf, Animal Resources & Compliance
Tel: 647-837-5844
Email: lise.phaneuf@phenogenomics.ca

Dr. Lauryl Nutter, Science & Technology Development
Tel: 416-813-7654 x 309565
Email: lauryl.nutter@sickkids.ca

Dr. John G. Sled, Mouse Imaging Centre (MICe)
Tel: 416-813-7654 x 309557
Email: john.sled@sickkids.ca

Dr. Colin McKerlie, Strategic Initiatives
Lead, Genome Canada Genomics Technology Platform
Tel: 416-813-7654 x309264
Email: colin.mckerlie@sickkids.ca

Managers


Owned and Operated by

Facility Partner for Infection & Inflammation

Funding Partners